AD | Applicability Domain |
ADME | Absorption, distribution, metabolism and excretion |
AE | Assessment Element |
AOP | Adverse Outcome Pathway |
AR | Androgen receptor |
ARN | Assessment of Regulatory Needs |
BFRs | Brominated Flame Retardants |
BP | Butylparaben |
BPR | Biocidal Products Regulation |
CAG | Cumulative Assessment Group |
CAS RN | Chemical Abstracts Service Registration Number |
CLP | Classification, Labelling and Packaging of substances and mixtures Regulation |
CLH | Harmonized Classification and Labelling |
CMR | Carcinogenic, Mutagenic or toxic for Reproduction |
CRA | Cumulative risk assessment |
DIO | Iodine-induced thyroid dysfunction |
DTU | Technical University of Denmark |
EATS | Estrogen, Androgen, Thyroid, Steroidogenesis |
ECHA | European Chemicals Agency |
ED | Endocrine Disruptor |
EFSA | European Food Safety Authority |
ER | Estrogen receptor |
GD | Guidance Document |
IC | Index compound |
IPB | Isobutylparaben (isobutyl 4-hydroxybenzoate) |
MoA | Mode of Action |
NIS | Sodium/Iodide symporter |
OECD | Organisation for Economic Co-operation and Development |
PBT/vPvB | Persistent, Bioaccumulative and Toxic/very Persistent, very Bioaccumulative |
PFAS | Per- and polyfluoroalkyl substances |
PMT/vPvM | Persistent, Mobile and Toxic/very Persistent, very Mobile |
PPPR | Plant Protection Products Regulation |
PXR | Pregnane X Receptor |
(Q)SARs | (Quantitative) Structure-Activity Relationships |
RAAF | Read-across Assessment Framework |
REACH | Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) Regulation |
SMILES | Simplified Molecular-Input Line-Entry System |
SVHC | Substance of Very High Concern |
Tox21/ToxCast | Toxicology in the 21st century/Toxicity Forecaster (chemical screening) |
TPO | Thyroid Peroxidase |
UVCB | Substance of Unknown or Variable composition, Complex reaction products or Biological materials |